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pentobarbital will lower the level or result of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital decreases levels of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can minimize panobinostat concentrations by ~70% and bring about p